Package: combiroc
Title: Selection and Ranking of Omics Biomarkers Combinations Made Easy
Date: 2023-07-04
Version: 0.3.4
Language: en-US
Authors@R: 
  c(person(given = "Ivan",
           family = "Ferrari",
           role = "aut",
           email = "ferrari@ingm.org",
           comment = c(ORCID = "0000-0003-3746-4143")),
    person(given = "Riccardo L.",
           family = "Rossi",
           role = c("aut", "cre"),
           email = "ric.rossi@gmail.com",
           comment = c(ORCID = "0000-0002-4964-3264")),
    person(given = "Saveria",
           family = "Mazzara",
           role = "aut",
           email = "saveria.mazzara@gmail.com",
           comment = c(ORCID = "0000-0003-1799-2360")),
    person(given = "Mauro",
           family = "Bombaci",
           role = c("ccp", "ctb", "dtc"),
           email = "bombaci@ingm.org",
           comment = c(ORCID = "0000-0002-9887-4165")))
Description: Provides functions and a workflow to easily and powerfully
        calculating specificity, sensitivity and ROC curves of
        biomarkers combinations. Allows to rank and select
        multi-markers signatures as well as to find the best performing
        sub-signatures, now also from single-cell RNA-seq datasets. The
        method used was first published as a Shiny app and described in
        Mazzara et al. (2017) <doi:10.1038/srep45477> and further
        described in Bombaci & Rossi (2019)
        <doi:10.1007/978-1-4939-9164-8_16>, and widely expanded as a
        package as presented in the bioRxiv pre print Ferrari et al.
        <doi:10.1101/2022.01.17.476603>.
License: MIT + file LICENSE
Encoding: UTF-8
LazyData: true
Roxygen: list(markdown = TRUE)
RoxygenNote: 7.2.3
Depends: R (>= 3.5.0)
Imports: tidyr, dplyr, ggplot2, gtools, pROC, stringr, stats, utils,
        moments
Suggests: testthat (>= 3.0.0), knitr, markdown, rmarkdown, httr, Seurat
VignetteBuilder: knitr
URL: https://doi.org/10.1101/2022.01.17.476603,
        https://github.com/ingmbioinfo/combiroc
BugReports: https://github.com/ingmbioinfo/combiroc/issues
Config/testthat/edition: 3
Config/pak/sysreqs: libicu-dev
Repository: https://ingmbioinfo.r-universe.dev
Date/Publication: 2026-01-07 10:07:34 UTC
RemoteUrl: https://github.com/ingmbioinfo/combiroc
RemoteRef: HEAD
RemoteSha: 93c57d501a84ad20dd7e3a9ba35c6aa6bc12b4ed
NeedsCompilation: no
Packaged: 2026-10-04 08:09:56 UTC; root
Author: Ivan Ferrari [aut] (ORCID: <https://orcid.org/0000-0003-3746-4143>),
  Riccardo L. Rossi [aut, cre] (ORCID:
    <https://orcid.org/0000-0002-4964-3264>),
  Saveria Mazzara [aut] (ORCID: <https://orcid.org/0000-0003-1799-2360>),
  Mauro Bombaci [ccp, ctb, dtc] (ORCID:
    <https://orcid.org/0000-0002-9887-4165>)
Maintainer: Riccardo L. Rossi <ric.rossi@gmail.com>